“I have been fascinated by animals since my childhood, and have a strong background in anatomy, behavior, molecular biology and awake electrophysiology. Since earning an independent position in Harvard University in 2013, my lab is interested in the functional organization of dopamine-striatum systems. Our current focuses include a unique subpopulation of dopamine neurons that project to the tail of the striatum (TS), computation of reward prediction error, and individual variability in the decision-making. My hobby now is to watch wild animals and to grow vegetables.”
Link to Uchida Lab here.
Selected publications:
| Striatal dopamine explains novelty-induced behavioral dynamics and individual variability in threat prediction K Akiti, I Tsutsui-Kimura, Y Xie, A Mathis, JE Markowitz, R Anyoha, Sandeep Robert Datta, Mackenzie Weygandt Mathis, Naoshige Uchida, Mitsuko Watabe-Uchida Neuron 110 (22), 3789-3804. | 2022 |
| A gradual temporal shift of dopamine responses mirrors the progression of temporal difference error in machine learning R Amo, S Matias, A Yamanaka, KF Tanaka, N Uchida, M Watabe-Uchida Nature neuroscience 25 (8), 1082-1092 | 2022 |
| Dynamical management of potential threats regulated by dopamine and direct-and indirect-pathway neurons in the tail of the striatum I Tsutsui-Kimura, N Uchida, M Watabe-Uchida bioRxiv, 2022.02. 05.479267 | 2022 |
| Distinct temporal difference error signals in dopamine axons in three regions of the striatum in a decision-making task I Tsutsui-Kimura, H Matsumoto, K Akiti, MM Yamada, N Uchida, Mitsuko Watabe-Uchida Elife 9, e62390 | 2020 |
| Dopamine neurons projecting to the posterior striatum reinforce avoidance of threatening stimuli W Menegas, K Akiti, R Amo, N Uchida, M Watabe-Uchida Nature neuroscience 21 (10), 1421-1430 | 2018 |
| Menegas, W., Babayan, B. M., Uchida, N., & Watabe-Uchida, M. (2017). Opposite initialization to novel cues in dopamine signaling in ventral and posterior striatum in mice. eLife , 6 e21886. | 2017 |
| Menegas, W., Bergan, J. F., Ogawa, S. K., Isogai, Y., Venkataraju, K. U., Osten, P., Uchida, N., & Watabe-Uchida, M. (2015). Dopamine neurons projecting to the posterior striatum form an anatomically distinct subclass. eLife , e10032. | 2015 |